In a large bowl, combine the ground beef, cheddar cheese, breadcrumbs, egg, Worcestershire sauce, garlic powder, onion powder, smoked paprika, salt, and pepper. Mix until well combined.
Form the mixture into four equal patties. Preheat a grill or skillet over medium-high heat and cook the patties for about 5-6 minutes on each side, or until they reach your desired doneness.
While the burgers are cooking, prepare the buns by toasting them lightly. Assemble the burgers by spreading mashed avocado on the bottom bun, adding the cooked patty, topping with bacon, lettuce, and tomato, and finishing with a dollop of mayonnaise before placing the top bun.